Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3857256 | 0.86 | CA1 (0.65) | FABP3FABP4CA1CA2HTR6 | |
| SCHEMBL13478762 | 0.86 | HTR6 (0.58) | FABP3FABP4CA1CA2HTR6 | |
| SCHEMBL13478768 | 0.83 | FABP3 (0.55) | FABP3FABP4CA1CA2HTR6 | |
| SCHEMBL1879091 | 0.82 | EGFR (0.42) | FABP3FABP4HTR6HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL1879366 | 0.82 | EGFR (0.44) | FABP3FABP4HTR6HDAC1HDAC6 | |
| SCHEMBL13478789 | 0.81 | FABP3 (0.59) | FABP3FABP4CA1CA2HTR6 | |
| SCHEMBL13478811 | 0.81 | FABP3 (0.53) | FABP3FABP4CA1CA2HTR6 | |
| SCHEMBL13478790 | 0.79 | SCARB1 (0.47) | FABP3FABP4CA1CA2HTR6 | |
| SCHEMBL13478771 | 0.79 | FABP3 (0.48) | FABP3FABP4CA1CA2HTR6 | |
| SCHEMBL14625203 | 0.79 | FABP3 (0.48) | FABP3FABP4CA1CA2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902026-B1 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | LILLY CO ELI (US) | 2010-02-17 | — | — | EP | disclosed |