Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 3/20 | 0.65 |
| ▸ | HTR6 | P50406 | 3/20 | 0.58 |
| ▸ | FABP4 | P15090 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478784 | 0.86 | FABP3 (0.55) | CA1CA2HTR6FABP4HDAC1 | |
| SCHEMBL7464584 | 0.85 | CA1 (0.67) | CA1CA2HTR6FABP4HDAC1 | |
| SCHEMBL6045346 | 0.83 | CA1 (0.94) | CA1CA2HTR6FABP4HDAC1 | |
| SCHEMBL4727325 | 0.80 | MAPT (0.59) | CA1CA2HTR6HDAC1HDAC6 | |
| SCHEMBL3853296 | 0.80 | CA1 (0.59) | CA1CA2HTR6FABP4HDAC1 | |
| SCHEMBL2244878 | 0.79 | CYP19A1 (0.60) | CA2HDAC1HDAC6LMNASMN1; SMN2 | |
| SCHEMBL31222301 | 0.79 | CYP19A1 (0.60) | CA2HDAC1HDAC6LMNASMN1; SMN2 | |
| SCHEMBL4193417 | 0.78 | SCARB1 (0.46) | CA1CA2HTR6HDAC1HDAC6 | |
| SCHEMBL3859121 | 0.77 | HTR6 (0.67) | CA1CA2HTR6FABP4PTGS1 | |
| Hydrochloric Acid SCHEMBL15267097 | 0.77 | HTR6 (0.58) | HTR6HTR1AHTR2AHTR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | CA1 2159/4885CA2 2739/4885HTR6 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.