Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996174 | 0.86 | KIF11 (0.47) | CA12CA1MMP2ALDH1A1EPHX2 | |
| SCHEMBL8996223 | 0.86 | KIF11 (0.47) | CA12CA1MMP2ALDH1A1EPHX2 | |
| SCHEMBL3266891 | 0.84 | CA12 (0.46) | CA12CA1MMP2EPHX2MEN1 | |
| SCHEMBL3266893 | 0.84 | CA12 (0.46) | CA12CA1MMP2EPHX2MEN1 | |
| SCHEMBL8996064 | 0.84 | CA12 (0.46) | CA12CA1MMP2EPHX2MEN1 | |
| SCHEMBL2703752 | 0.81 | CA12 (0.44) | CA12MMP2ALDH1A1L3MBTL1FFAR1 | |
| SCHEMBL1734546 | 0.81 | CA12 (0.46) | CA12CA1MMP2ALDH1A1EPHX2 | |
| SCHEMBL1734544 | 0.81 | CA12 (0.46) | CA12CA1MMP2ALDH1A1EPHX2 | |
| SCHEMBL13611381 | 0.81 | FPR2 (0.50) | CA12CA1MMP2EPHX2L3MBTL1 | |
| SCHEMBL8996273 | 0.80 | CA12 (0.42) | CA12CA1MMP2EPHX2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2154132-A1 | A process for preparing tetrahydroquinoline derivatives | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-02-17 | — | — | EP | disclosed |