Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PPM1B | O75688 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458051 | 0.91 | CHRNB2 (0.49) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL23688029 | 0.91 | CHRNB2 (0.49) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL19284970 | 0.91 | CHRNB2 (0.49) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL22230562 | 0.91 | CHRNB2 (0.49) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL21306551 | 0.82 | CHRNB2 (0.52) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL29820048 | 0.82 | CHRNB2 (0.52) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL7909093 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL8885874 | 0.81 | CHRNB2 (0.51) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| Methyl Benzoate SCHEMBL27875044 | 0.79 | TSHR (0.47) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL22005207 | 0.78 | CARM1 (0.58) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655699-B1 | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors | EISAI INC. (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655699-B1 | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors | EISAI INC. (US) | 2010-02-02 | — | — | US | disclosed |