Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 8/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87663 | 0.77 | F10 (0.66) | F10F2 | |
| SCHEMBL87704 | 0.76 | F10 (0.65) | F10F2 | |
| SCHEMBL13479590 | 0.74 | NPSR1 (0.46) | ALDH1A1HPGDKDM4ELMNAF10 | |
| SCHEMBL8246133 | 0.74 | NPSR1 (0.44) | ALDH1A1HPGDKDM4ELMNAF10 | |
| SCHEMBL8244920 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EF10MEN1 | |
| SCHEMBL15500429 | 0.71 | KDM4E (0.42) | ALDH1A1HPGDKDM4EF10MAPT | |
| SCHEMBL87333 | 0.69 | F10 (0.68) | F10F2 | |
| SCHEMBL8361475 | 0.68 | NPSR1 (0.42) | ALDH1A1HPGDKDM4ELMNAF10 | |
| SCHEMBL78813 | 0.68 | F10 (0.48) | ALDH1A1HPGDKDM4ELMNAF10 | |
| SCHEMBL87227 | 0.67 | F10 (0.71) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411932-B1 | SUBSTITUTED OXAZOLIDINONES FOR COMBINATIONAL THERAPY | BAYER SCHERING PHARMA AG (DE) | 2010-02-10 | — | — | EP | disclosed |