Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13479590 | 0.98 | NPSR1 (0.46) | NPSR1SMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL8361475 | 0.88 | NPSR1 (0.42) | NPSR1SMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL8244920 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDF10KMT2A | |
| SCHEMBL78813 | 0.82 | F10 (0.48) | NPSR1SMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL87218 | 0.77 | F10 (0.68) | F10 | |
| SCHEMBL8215265 | 0.77 | F10 (0.67) | F10 | |
| SCHEMBL87173 | 0.76 | F10 (0.68) | F10 | |
| SCHEMBL15500462 | 0.76 | F10 (0.44) | SMN1; SMN2NPC1F10TSHRMAPK1 | |
| SCHEMBL13093562 | 0.75 | F10 (0.47) | NPSR1SMN1; SMN2F10TSHRKMT2A | |
| SCHEMBL13479697 | 0.74 | ALDH1A1 (0.41) | NPSR1ALDH1A1KDM4EHPGDF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039134-A1 | COMBINATION THERAPY COMPRISING SUBSTITUTED OXAZOLIDINONES FOR THE PREVENTION AND TREATMENT OF CEREBRAL CIRCULATORY DISORDERS | BAYER HEALTHCARE AG (DE) | 2007-04-12 | — | — | WO | disclosed |