Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25641436 | 0.85 | CYP1A2 (0.42) | CYP1A2CYP2D6 | |
| SCHEMBL13658057 | 0.85 | CYP1A2 (0.42) | CYP1A2CYP2D6 | |
| SCHEMBL28495821 | 0.78 | CHRNB2 (0.41) | CYP1A2CYP2D6 | |
| SCHEMBL20972363 | 0.78 | CYP1A2 (0.45) | CYP1A2CYP2D6 | |
| SCHEMBL10163498 | 0.77 | CYP1A2 (0.46) | CYP1A2CYP2D6 | |
| SCHEMBL8814526 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP2D6 | |
| SCHEMBL10774598 | 0.75 | CA1 (0.36) | UGT2B7 | |
| SCHEMBL18543679 | 0.73 | CA1 (0.34) | UGT2B7 | |
| SCHEMBL19884708 | 0.73 | — | — | |
| SCHEMBL9637783 | 0.72 | CA1 (0.45) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701956-B1 | PYRROLO[2,3-B]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2010-02-24 | — | — | EP | disclosed |