Thiobutyrolactone

Thiobutyrolactone

SCHEMBL13480

O=C1CCCS1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobutyrolactone SCHEMBL1021969 1.00
SCHEMBL1026885 0.90
SCHEMBL1024355 0.90
Hydrochloric Acid SCHEMBL17701165 0.88 ALDH1A1 (0.37)
SCHEMBL19484930 0.88 ALDH1A1 (0.40)
SCHEMBL23572609 0.88 ALDH1A1 (0.40)
SCHEMBL1024258 0.88
SCHEMBL19485084 0.88 ALDH1A1 (0.40)
SCHEMBL1023901 0.88
SCHEMBL1024256 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5099 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4194092-B1 SYNTHESIS AND CHARACTERIZATION OF METATHESIS CATALYSTS UMICORE AG & CO KG (DE) 2025-10-22 EP claimed
EP-4605121-A1 DELIVERY PARTICLES BASED ON AMINE-THIOL-ENE CONJUGATES AND DERIVATIVES Encapsys, LLC (US) 2025-08-27 EP claimed
WO-2024086501-A9 DELIVERY PARTICLES BASED ON AMINE-THIOL-ENE CONJUGATES AND DERIVATIVES ENCAPSYS, LLC (US) 2024-12-26 WO claimed
EP-4240579-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-04 EP claimed
US-20240335375-A1 MUCOADHESIVE OCULAR DELIVERY SYSTEM FOR THE TREATMENT OF GLAUCOMA BIOADHESIVE OPHTHALMICS (FR) 2024-10-10 US claimed
EP-4380545-A1 MUCOADHESIVE OCULAR DELIVERY SYSTEM FOR THE TREATMENT OF GLAUCOMA Bioadhésive Ophthalmics (FR) 2024-06-12 EP claimed
WO-2024086501-A1 DELIVERY PARTICLES BASED ON AMINE-THIOL-ENE CONJUGATES AND DERIVATIVES ENCAPSYS, LLC (US) 2024-04-25 WO claimed
US-11958042-B2 Reactions of olefin derivatives in the presence of metathesis catalysts UMICORE AG & CO. KG (DE) 2024-04-16 US claimed
US-11848396-B2 Surfactant additive for solution coating large area high efficiency perovskite solar cells and other devices NUTECH VENTURES, INC. (US) 2023-12-19 US claimed
CN-117241669-A Cyclopropylamide compounds against parasites in fish 英特威国际有限公司荷兰疫苗厂 2023-12-15 CN claimed
EP-0293503-B1 UREA STABILIZED WITH A LACTONE IN VARIOUS PHARMACEUTICAL AND COSMETIC PREPARATIONS Key Pharmaceuticals, Inc. (US) 1992-04-08 EP claimed
WO-1992004353-A1 CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES BEECHAM GROUP PLC (GB) 1992-03-19 WO claimed
US-5035978-A Containing tone-controlling sulfur compound EASTMAN KODAK COMPANY (US) 1991-07-30 US claimed
EP-0368763-A1 4-Mercapto butyramides N-mono or N,N-disubstituted by a mono or polyhydroxyalkyl radical, and their use as reducing agents in the process of permanent deformation of the hair L'OREAL (FR) 1990-05-16 EP claimed
EP-0293503-A1 Urea stabilized with a lactone in various pharmaceutical and cosmetic preparations Key Pharmaceuticals, Inc. (US) 1988-12-07 EP claimed
US-4656233-A \"Living\" polymers and chain transfer-regulated polymerization process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-07 US claimed
EP-0028161-B1 FLUORINATED PHENOLIC POLYMER AND PROCESS FOR ITS PREPARATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-21 EP claimed
US-4321339-A Fluorinated phenoxypropyl vinyl ether polymer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-23 US claimed
EP-0028161-A1 Fluorinated phenolic polymer and process for its preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-06 EP claimed
US-4120866-A REACTING AN AROMATIC COMPOUND WITH A SULFOXIDE BAYER AKTIENGESELLSCHAFT (DE) 1978-10-17 US claimed