Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.65 |
| ▸ | RXRG | P48443 | 12/20 | 0.65 |
| ▸ | RXRB | P28702 | 11/20 | 0.65 |
| ▸ | RARG | P13631 | 7/20 | 0.65 |
| ▸ | RARB | P10826 | 6/20 | 0.65 |
| ▸ | RARA | P10276 | 4/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533586 | 0.82 | RXRA (0.68) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL13846941 | 0.82 | RXRA (0.59) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL13745116 | 0.80 | RXRA (0.64) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL29357483 | 0.79 | RXRA (1.00) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL301213 | 0.79 | RXRA (1.00) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL13752425 | 0.79 | RXRA (0.82) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL29434832 | 0.79 | RXRA (1.00) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL14068162 | 0.77 | RXRA (0.65) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7023688 | 0.77 | RXRA (0.71) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL6889517 | 0.76 | RXRA (0.73) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655699-B1 | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors | EISAI INC. (US) | 2010-02-02 | — | — | US | disclosed |