Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 1.00 |
| ▸ | RXRB | P28702 | 9/20 | 1.00 |
| ▸ | RXRG | P48443 | 9/20 | 1.00 |
| ▸ | RARB | P10826 | 6/20 | 1.00 |
| ▸ | RARG | P13631 | 6/20 | 1.00 |
| ▸ | RARA | P10276 | 5/20 | 1.00 |
| ▸ | PPARG | P37231 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357483 | 1.00 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL301213 | 1.00 | RXRA (1.00) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL13752425 | 0.90 | RXRA (0.82) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL14816552 | 0.89 | RXRA (0.80) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL20411355 | 0.88 | RXRA (0.78) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1073361 | 0.87 | RXRA (0.77) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6376581 | 0.86 | RXRA (0.76) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL21549712 | 0.85 | RXRA (0.74) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6889517 | 0.85 | RXRA (0.73) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL14816543 | 0.83 | RXRA (0.71) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2025024484-A1 | COMPOSITIONS AND METHODS FOR TREATING BLOOD CANCER | DUKE UNIVERSITY (US) | 2025-01-30 | — | — | WO | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-109715637-B | Glucokinase activators and methods of use thereof | 百时美施贵宝公司 | 2022-04-05 | — | — | CN | disclosed |