Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180536 | 1.00 | L3MBTL1 (0.52) | L3MBTL1HSP90AA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3194699 | 1.00 | L3MBTL1 (0.52) | L3MBTL1HSP90AA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3180518 | 1.00 | L3MBTL1 (0.52) | L3MBTL1HSP90AA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3179411 | 0.81 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL13480838 | 0.81 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3179405 | 0.81 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7172086 | 0.81 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL6061340 | 0.81 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL5241683 | 0.81 | TP53 (0.51) | L3MBTL1HSP90AA1ALDH1A1CYP2C19MAPT | |
| SCHEMBL15836588 | 0.80 | MEN1 (0.65) | L3MBTL1ALDH1A1CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655689-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655689-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7517904-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| US-7517904-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |