Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 16/20 | 0.54 |
| ▸ | CA1 | P00915 | 14/20 | 0.54 |
| ▸ | CA2 | P00918 | 14/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14393164 | 0.86 | USP2 (0.73) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL2755000 | 0.80 | USP2 (0.68) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL1437042 | 0.80 | USP2 (0.78) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL20254033 | 0.80 | USP2 (0.77) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL10098714 | 0.79 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL3481432 | 0.79 | USP2 (1.00) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL30023431 | 0.79 | USP2 (1.00) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL18239274 | 0.79 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL29591827 | 0.79 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL107875 | 0.79 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7658917-B2 | Modulators of amyloid aggregation | PRAECIS PHARMACEUTICALS, INC. (US) | 2010-02-09 | — | — | US | disclosed |