SCHEMBL1348353

SCHEMBL1348353

O=[N+]([O-])CC(O)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.67
NPC1 O15118 2/20 0.51
ADAM17 P78536 1/20 0.51
CPA1 P15085 3/20 0.49
LMNA P02545 1/20 0.48
BCAT2 O15382 1/20 0.47
KDM4E B2RXH2 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GSR P00390 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
AOC3 Q16853 3/20 0.44
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5521085 1.00 ALDH1A1 (0.67) ALDH1A1NPC1ADAM17CPA1LMNA
SCHEMBL6256630 1.00 ALDH1A1 (0.67) ALDH1A1NPC1ADAM17CPA1LMNA
SCHEMBL17977235 0.89 ALDH1A1 (0.64) ALDH1A1NPC1ADAM17CPA1LMNA
SCHEMBL27807830 0.82 ALDH1A1 (0.70) ALDH1A1NPC1LMNAKDM4EMAPT
SCHEMBL27807831 0.82 ALDH1A1 (0.70) ALDH1A1NPC1LMNAKDM4EMAPT
SCHEMBL9202581 0.80 NPC1 (0.56) ALDH1A1NPC1ADAM17CPA1KDM4E
SCHEMBL2461328 0.80 ALDH1A1 (0.68) ALDH1A1NPC1LMNAKDM4EMAPT
SCHEMBL4242515 0.80 ALDH1A1 (1.00) ALDH1A1NPC1LMNAKDM4EMAPT
SCHEMBL2461281 0.80 ALDH1A1 (0.68) ALDH1A1NPC1LMNAKDM4EMAPT
SCHEMBL11947918 0.80 ALDH1A1 (0.62) ALDH1A1NPC1CPA1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096117-B Preparation method of 1-phenyl-2-nitroethanol and derivatives thereof 南京信息工程大学 2020-12-25 CN claimed
CN-109096117-A The preparation method of 1- phenyl -2- nitroethyl alcohol and its derivative 南京信息工程大学 2018-12-28 CN claimed
CN-108821995-A Chiral tetrahedron-type metal cluster, metal composite and its preparation method and application 中国科学技术大学 2018-11-16 CN claimed
CN-103601654-B A kind of preparation method of taurine substitute HUANGGANG FUCHI PHARMACEUTICAL CO., LTD. (CN) 2015-12-09 CN claimed
CN-105111086-A 1-phenyl-2-nitroethanol and preparation method of derivatives thereof UNIV NANJING INF SCI & TECH 2015-12-02 CN claimed
CN-103450229-B Application of chiral copper complex LUO MEI 2015-04-29 CN claimed
CN-102399160-B Method for synthesizing chloramphenicol WUHAN WU PHARMACEUTICAL TECHNOLOGY CO LTD 2014-07-16 CN claimed
CN-102399161-B Method for preparing chloramphenicol WUHAN WU PHARMACEUTICAL TECHNOLOGY CO LTD 2014-07-16 CN claimed
CN-102174125-B Preparation and application of novel CH2-N=C-Ar group-modified cyclodextrin derivatives BEIJING INST TECHNOLOGY 2013-01-02 CN claimed
CN-102399160-A Synthesis method of chloramphenicol WUHAN WU PHARMACEUTICAL TECHNOLOGY CO LTD 2012-04-04 CN claimed
CN-102399161-A Preparation method of chloramphenicol WUHAN WU PHARMACEUTICAL TECHNOLOGY CO LTD 2012-04-04 CN claimed
JP-58203950-A None JP disclosed
CN-117466742-A Method for synthesizing beta-nitroalcohol by using alcohol compound as initial raw material through one-pot method 扬州工业职业技术学院 2024-01-30 CN disclosed
CN-116782894-A Lactam compounds as Kv1.3 potassium Shaker channel blockers D.E.肖研究有限责任公司 2023-09-19 CN disclosed
CN-113087728-A Copper complex 合肥工业大学 2021-07-09 CN disclosed
US-5428172-A Preparation of 3-dihaloacetyl oxazolidines MONSANTO COMPANY (US) 1995-06-27 US disclosed
EP-0648768-A1 Preparation of 3-dihaloacetyl oxazolidines MONSANTO COMPANY (US) 1995-04-19 EP disclosed
US-5137929-A Additives which stabilize hydrohalocarbon blowing agent in polyurethane and polyisocyanurate foam formulations during polymerization ALLIED-SIGNAL INC. (US) 1992-08-11 US disclosed
JP-S58203950-A PREPARATION OF ALPHA-AMINOMETHYLBENZYL ALCOHOL DERIVATIVE OTA SEIYAKU KK 1983-11-28 JP disclosed
US-4160035-A 1-PHENYL-2-NITRO-1,3-PROPANEDIOL DIESTERS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1979-07-03 US disclosed