Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | METAP2 | P50579 | 3/20 | 0.66 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CCR9 | P51686 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220857 | 0.94 | LMNA (0.81) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL2534878 | 0.89 | LMNA (0.86) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL2003387 | 0.87 | METAP2 (0.77) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL16479406 | 0.87 | LMNA (0.68) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL16479405 | 0.87 | LMNA (0.71) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL13077403 | 0.86 | BDKRB1 (0.64) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL28289991 | 0.86 | BDKRB1 (0.74) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL28518 | 0.85 | LMNA (0.80) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL14215454 | 0.85 | LMNA (0.65) | LMNAHTTTP53MAPTKMT2A | |
| SCHEMBL13077434 | 0.85 | LMNA (0.65) | LMNAHTTTP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659272-B2 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-02-09 | — | — | US | disclosed |