SCHEMBL1348468

SCHEMBL1348468

[CH2]OCc1cccc(N)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.52
MAOA P21397 2/20 0.52
CYP19A1 P11511 1/20 0.50
CYP3A4 P08684 3/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
CA12 O43570 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
APP P05067 1/20 0.41
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366865 0.82 MAOB (0.56) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL1520696 0.80 IDO1 (0.61) MAOBMAOACYP3A4IDO1AGXT
SCHEMBL18217412 0.78 MAOB (0.52) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL27399787 0.78 MAOB (0.52) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL9401852 0.78 MAOB (0.52) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL30601044 0.78 MAOB (0.52) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL633486 0.78 MAOB (0.52) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL27532081 0.78 MAOB (0.47) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL5165545 0.78 MAOB (0.47) MAOBMAOACYP19A1CYP3A4CASP1
SCHEMBL7692759 0.78 MAOB (0.47) MAOBMAOACYP19A1CYP3A4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4139346-A Nucleic acid and protein binding paper ENZO BIO CHEM INCORPORATED (US) 1979-02-13 US claimed
EP-1824600-B1 FLUID PROCESSING DEVICE INCLUDING SIZE-CHANGING BARRIER LIFE TECHNOLOGIES CORP (US) 2016-12-28 EP disclosed
EP-1828746-B1 FLUID PROCESSING DEVICE INCLUDING COMPOSITE MATERIAL FLOW MODULATOR LIFE TECHNOLOGIES CORP (US) 2016-12-28 EP disclosed
US-8383062-B2 Fluid processing device including size-changing barrier APPLIED BIOSYSTEMS, LLC (US) 2013-02-26 US disclosed
US-8062611-B2 Fluid processing device including composite material flow modulator APPLIED BIOSYSTEMS, LLC (US) 2011-11-22 US disclosed
US-20110114206-A1 Fluid Processing Device Including Size-Changing Barrier Life Technologies Corporation (US) 2011-05-19 US disclosed
US-20100133104-A1 Fluid processing device including size-changing barrier Life Technologies Corporation (US) 2010-06-03 US disclosed
US-20060093526-A1 Fluid processing device including composite material flow modulator APPLERA CORPORATION (US) 2006-05-04 US disclosed
US-20060090800-A1 Fluid processing device including size-changing barrier APPLERA CORPORATION (US) 2006-05-04 US disclosed
US-6773701-B2 AN GENE EXPRESSION ENHANCER COMPRISING A MIXTURE OF HUMAN INTERFERON- ALPHA 2 AND INTERFERON- ALPHA 8 SUBTYPES KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2004-08-10 US disclosed
EP-0164876-A1 Displacement polynucleotide assay employing recombination protein and diagnostic kit ALLIED CORPORATION (US) 1985-12-18 EP disclosed
EP-0108633-A2 Assay for qualitatively and/or quantitatively measuring hLH or hCG in body fluids and reagents therefor CORNELL RESEARCH FOUNDATION, INC. (US) 1984-05-16 EP disclosed
US-RE31006-E COUPLING WITH ENZYME AKZONA INCORPORATED (US) 1982-08-03 US disclosed
US-4286964-A Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates SEED BRIAN S 1981-09-01 US disclosed
EP-0027377-A1 Derivatives of hydroxyl-bearing substrates, process for their preparation and a method of application Seed, Brian Sarsfield (US) 1981-04-22 EP disclosed
US-4188371-A CONTACTING RADIOLABELLED ANTISERUM SPECIFIC TO 1,2-PROPANEDIOL DEHYDROGENASE WITH SAMPLE LYSATE, INCUBATING, CONTACTING WITH SOLID PHASE ANTIGEN OR ANTIGEN IMMUNOADSORBENT, INCUBATING, MONITORING CORNING GLASS WORKS (US) 1980-02-12 US disclosed
US-4139346-A Nucleic acid and protein binding paper ENZO BIO CHEM INCORPORATED (US) 1979-02-13 US disclosed
US-4138292-A ENZYMES OR MICROORGANISMS IN A SULFATED POLYSACCHARIDE GEL TANABE SEIYAKU CO., LTD. (JP) 1979-02-06 US disclosed
US-4016043-A Enzymatic immunological method for the determination of antigens and antibodies AKZONA INCORPORATED (US) 1977-04-05 US disclosed
US-RE29169-E PROTEINS, ENZYMES AKZONA INCORPORATED (US) 1977-04-05 US disclosed