Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601044 | 1.00 | MAOB (0.52) | MAOBMAOACYP19A1CYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6320078 | 0.98 | MAOB (0.53) | MAOBMAOACYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL487468 | 0.84 | IDO1 (0.48) | MAOBCYP3A4IDO1AGXT | |
| SCHEMBL8256843 | 0.83 | MAOB (0.44) | MAOBMAOACYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL30041293 | 0.83 | MAOB (0.44) | MAOBMAOACYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL366865 | 0.82 | MAOB (0.56) | MAOBMAOACYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL1520696 | 0.80 | IDO1 (0.61) | MAOBMAOACYP3A4IDO1AGXT | |
| SCHEMBL29684100 | 0.79 | MAOB (0.59) | MAOBMAOACYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL6678878 | 0.79 | MAOB (0.59) | MAOBMAOACYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL8011823 | 0.79 | CYP3A4 (0.50) | MAOBMAOACYP19A1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844044-B1 | THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-07-21 | — | — | EP | claimed |
| US-7678815-B2 | Thiazole-4-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1844044-A1 | THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-17 | — | — | EP | claimed |
| US-20060160857-A1 | Thiazole-4-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. | 2006-07-20 | — | — | US | claimed |
| WO-2006074884-A1 | THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-07-20 | — | — | WO | claimed |
| US-4139346-A | Nucleic acid and protein binding paper | ENZO BIO CHEM INCORPORATED (US) | 1979-02-13 | — | — | US | claimed |
| US-12486258-B2 | Compounds and methods for regulating insulin secretion | THE BROAD INSTITUTE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| US-20250115581-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2025-04-10 | — | — | US | disclosed |
| CN-118909239-A | Preparation method and application of polyether polyol for adhesive | 江苏钟山新材料有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114315796-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| US-20230192607-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | THE BROAD INSTITUTE, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-4286964-A | Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates | SEED BRIAN S | 1981-09-01 | — | — | US | disclosed |
| EP-0027377-A1 | Derivatives of hydroxyl-bearing substrates, process for their preparation and a method of application | Seed, Brian Sarsfield (US) | 1981-04-22 | — | — | EP | disclosed |
| US-4188371-A | CONTACTING RADIOLABELLED ANTISERUM SPECIFIC TO 1,2-PROPANEDIOL DEHYDROGENASE WITH SAMPLE LYSATE, INCUBATING, CONTACTING WITH SOLID PHASE ANTIGEN OR ANTIGEN IMMUNOADSORBENT, INCUBATING, MONITORING | CORNING GLASS WORKS (US) | 1980-02-12 | — | — | US | disclosed |
| US-4139346-A | Nucleic acid and protein binding paper | ENZO BIO CHEM INCORPORATED (US) | 1979-02-13 | — | — | US | disclosed |
| US-4138292-A | ENZYMES OR MICROORGANISMS IN A SULFATED POLYSACCHARIDE GEL | TANABE SEIYAKU CO., LTD. (JP) | 1979-02-06 | — | — | US | disclosed |
| US-4016043-A | Enzymatic immunological method for the determination of antigens and antibodies | AKZONA INCORPORATED (US) | 1977-04-05 | — | — | US | disclosed |
| US-RE29169-E | PROTEINS, ENZYMES | AKZONA INCORPORATED (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142508-A1 | COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION | IAPP, GPR119, PNLIP | MAOB 3316/4885MAOA 3998/4885CYP19A1 2131/4885 |
| US-20060160857-A1 | Thiazole-4-carboxyamide derivatives | GRM1, GRM2, GRIA4 | MAOB 3622/4885MAOA 3677/4885CYP19A1 3116/4885 |
| US-20250115581-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | CKS1B, CSNK1A1, CKS2 | MAOB 4157/4885MAOA 3159/4885CYP19A1 817/4885 |
| US-12486258-B2 | Compounds and methods for regulating insulin secretion | IAPP, GPR119, PNLIP | MAOB 3316/4885MAOA 3998/4885CYP19A1 2131/4885 |
| US-20230192607-A1 | TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF | TEAD1, TEAD4, TEAD2 | MAOB 3216/4885MAOA 3448/4885CYP19A1 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.