Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366865 | 0.82 | MAOB (0.56) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL1520696 | 0.80 | IDO1 (0.61) | MAOBMAOACYP3A4IDO1AGXT | |
| SCHEMBL9401852 | 0.78 | MAOB (0.52) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL18217412 | 0.78 | MAOB (0.52) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL1348468 | 0.78 | MAOB (0.52) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL633486 | 0.78 | MAOB (0.52) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL30601044 | 0.78 | MAOB (0.52) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL21921202 | 0.78 | MAOB (0.47) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL21838316 | 0.78 | MAOB (0.47) | MAOBMAOACYP19A1CA12ALDH1A1 | |
| SCHEMBL17028590 | 0.77 | ENPP2 (0.58) | CA12ALDH1A1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064360-C | Fused imidazo [1, 2-a ] pyridines | SHINIPPON PHARMACEUTICAL INC (JP) | 2001-04-11 | — | — | CN | disclosed |