SCHEMBL134856

SCHEMBL134856

COc1cccc(C)c1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
NFE2L2 Q16236 5/20 0.47
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 2/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28264941 0.98 SMN1; SMN2 (0.50) SMN1; SMN2CA12CA1CA2CA4
Bicarbonate SCHEMBL27404233 0.89 CA12 (0.53) SMN1; SMN2CA12CA1CA2CA7
SCHEMBL11358465 0.88 CA12 (0.42) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL11123445 0.85 CA1 (0.52) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL25434306 0.84 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL27753904 0.84 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL151213 0.84 CA1 (0.61) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL145464 0.84 ALDH1A1 (0.48) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL5399317 0.82 SMN1; SMN2 (0.48) SMN1; SMN2CA12CA1CA2CA4
SCHEMBL14120688 0.82 CA12 (0.37) SMN1; SMN2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119999908-A Novel oil-soluble precursor micelle preparation and production method thereof 酰莱(合肥)生命科学研发有限公司 2025-05-16 CN claimed
CN-120000585-A Novel drug-assisted precursor micelle preparation and production method thereof 酰莱(合肥)生命科学研发有限公司 2025-05-16 CN claimed
EP-3274377-B1 CATALYST SYSTEM AND PROCESS FOR THE PRODUCTION OF POLYETHYLENES SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-09-06 EP claimed
CN-107278210-B Catalyst system and process for producing polyethylene SABIC环球技术有限责任公司 2020-12-15 CN claimed
US-10472439-B2 Catalyst system and process for the production of polyethylenes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-12 US claimed
CN-109481444-A A kind of taxol and phthalazines class BTK inhibitor drug combination compositions and its application 南京先进生物材料与过程装备研究院有限公司 2019-03-19 CN claimed
CN-109481442-A A kind of taxol and adjacent phenyl phthalazines ketone BTK inhibitor drug combination compositions and its application 南京先进生物材料与过程装备研究院有限公司 2019-03-19 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
CN-109394765-A A kind of taxol and to phenyl phthalazines ketone BTK inhibitor drug combination compositions and its application 南京先进生物材料与过程装备研究院有限公司 2019-03-01 CN claimed
EP-3197924-B1 A CONTINUOUS PROCESS FOR THE PRODUCTION OF ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-01-23 EP claimed
CN-1350458-A Protease inhibitors SMITHKLINE BEECHAM CORP (US) 2002-05-22 CN claimed
EP-1155001-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 2001-11-21 EP claimed
WO-2000050406-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2000-08-31 WO claimed
CN-1255367-A Compsns. for recovering and promoting skin protective functions and its evaluating method SHISEIDO CO LTD (JP) 2000-06-07 CN claimed
US-6060453-A Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose GREENWICH PHARMACEUTICALS INCORPORATED (US) 2000-05-09 US claimed
EP-0834507-A1 Substituted diamino-1,3,5-triazine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1998-04-08 EP claimed
EP-0500530-B1 CATALYST COMPONENT FOR MAKING PRIMARILY ISOTACTIC ELASTOMERIC POLYPROPYLENE OR POLYBUTENE SHELL OIL CO (US) 1996-09-11 EP claimed
US-4971936-A COORDINATION CATALYST OF MAGNESIUM ALKOXIDE, TETRAVALENT TITANIUM HALIDE AND VERATROLE SHELL OIL COMPANY (US) 1990-11-20 US claimed
US-4808497-A WITH DIETHER SOLVENT EVEREADY BATTERY COMPANY (US) 1989-02-28 US claimed
US-4272634-A Process for the production of intermediate oxidation products of toluenes having ether linkages DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1981-06-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR SMN1; SMN2 4265/4885CA12 299/4885CA1 140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.