Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806276 | 0.84 | PIP4K2A (0.40) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL13184308 | 0.84 | KMT2A (0.38) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL21128745 | 0.84 | LMNA (0.33) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL29303426 | 0.84 | LMNA (0.33) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL21128743 | 0.84 | LMNA (0.33) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL16006453 | 0.84 | KMT2A (0.38) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL21608555 | 0.84 | PI4KA (0.38) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL29303150 | 0.81 | GPR55 (0.36) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL25638413 | 0.81 | LMNA (0.32) | HPGDHTTLMNAMAPK1TP53 | |
| SCHEMBL29956343 | 0.81 | PI4KA (0.33) | HPGDHTTLMNAMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072270-A1 | PROTAC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | 百极弘烨(南通)医药科技有限公司 | 2023-05-04 | — | — | WO | disclosed |
| US-20100032624-A1 | INDAZOLE COMPOUND-CONTAINING COMPOSITION AND LIGHT-EMITTING DEVICE USING THE COMPOSITION | SUMITOMO CHEMCIAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |