Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495503 | 0.90 | TSHR (0.50) | TSHRHRH3CYP3A4ADRB2ADRB1 | |
| SCHEMBL1755590 | 0.88 | TSHR (0.48) | TSHRHRH3CYP3A4ADRB2ADRB1 | |
| SCHEMBL6178247 | 0.84 | HRH3 (0.34) | HRH3ALDH1A1 | |
| SCHEMBL2182488 | 0.83 | HTT (0.48) | TSHRHRH3CYP3A4MEN1THRB | |
| SCHEMBL20256087 | 0.82 | TSHR (0.38) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL302981 | 0.82 | TSHR (0.55) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL2280804 | 0.81 | HTT (0.52) | TSHRHRH3MEN1THRBHTT | |
| SCHEMBL18503217 | 0.81 | HTT (0.52) | TSHRHRH3MEN1THRBHTT | |
| SCHEMBL18503196 | 0.81 | HTT (0.52) | TSHRHRH3MEN1THRBHTT | |
| SCHEMBL18503150 | 0.81 | HTT (0.52) | TSHRHRH3MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036136-A1 | Maleimide Containing Ester and Sulfide Functionalities | HENKEL AG & CO. KGAA (DE) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036136-A1 | Maleimide Containing Ester and Sulfide Functionalities | EPCAM, ILK, TST | TSHR 4132/4885HRH3 4115/4885CYP3A4 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.