Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493603 | 1.00 | LMNA (0.50) | LMNAL3MBTL1NOX1GRIN2DGRIN3B | |
| SCHEMBL1492173 | 1.00 | LMNA (0.50) | LMNAL3MBTL1NOX1GRIN2DGRIN3B | |
| SCHEMBL11529245 | 0.88 | IDO1 (0.47) | LMNAL3MBTL1GRIN1GRIN2BMEN1 | |
| SCHEMBL13133358 | 0.86 | NFE2L2 (0.47) | LMNAL3MBTL1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1492138 | 0.86 | MAPT (0.49) | L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1492136 | 0.86 | MAPT (0.49) | L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1492206 | 0.86 | MAPT (0.49) | LMNAL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL1492203 | 0.86 | MAPT (0.49) | LMNAL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL1492109 | 0.86 | SMN1; SMN2 (0.48) | LMNAL3MBTL1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1492112 | 0.86 | SMN1; SMN2 (0.48) | LMNAL3MBTL1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642812-B2 | Frustrated Lewis pair compositions | STEPHAN CONSULTING CORPORATION (CA) | 2014-02-04 | — | — | US | disclosed |
| US-20130018207-A1 | Frustrated Lewis Pair Compositions | STEPHAN CONSULTING CORPORATION (CA) | 2013-01-17 | — | — | US | disclosed |
| US-8299284-B2 | Frustrated lewis pair compositions | STEPHAN CONSULTING CORPORATION (CA) | 2012-10-30 | — | — | US | disclosed |
| US-20100048949-A1 | HYDROGEN SPLITTING COMPOSITION | STEPHAN CONSULTING CORPORATION (CA) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018207-A1 | Frustrated Lewis Pair Compositions | LPAR3, SSTR3, LPAR1 | LMNA 2047/4885L3MBTL1 950/4885NOX1 1986/4885 |
| US-20100048949-A1 | HYDROGEN SPLITTING COMPOSITION | SSTR3, FFAR3, SSTR1 | LMNA 2276/4885L3MBTL1 2072/4885NOX1 2951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.