Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28163245 | 0.85 | DPP4 (0.33) | AAK1DPP4CA1CA2CA7 | |
| SCHEMBL3244669 | 0.81 | DPP4 (0.33) | AAK1DPP4 | |
| SCHEMBL38666150 | 0.81 | DPP4 (0.33) | AAK1DPP4 | |
| SCHEMBL6971708 | 0.79 | USP30 (0.31) | USP30 | |
| SCHEMBL18714767 | 0.75 | MMP13 (0.31) | AAK1 | |
| SCHEMBL21964901 | 0.75 | CA1 (0.35) | AAK1DPP4CA1CA2CA7 | |
| SCHEMBL5345861 | 0.74 | AAK1 (0.35) | AAK1CA1CA2CA7USP30 | |
| SCHEMBL7060767 | 0.74 | AAK1 (0.33) | AAK1CA1CA2CA7CTSD | |
| SCHEMBL21104426 | 0.74 | AAK1 (0.33) | AAK1 | |
| SCHEMBL7060773 | 0.74 | AAK1 (0.33) | AAK1CA1CA2CA7CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047841-A1 | SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047841-A1 | SYNTHESIS OF DESACETOXYTUBULYSIN H AND ANALOGS THEREOF | XDH, XPA, TPX2 | AAK1 2623/4885DPP4 3874/4885CA1 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.