SCHEMBL13490502

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL171619	0.81	PDE2A (0.55)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL15352774	0.78	DRD2 (0.49)	DRD2DRD4DRD3
	SCHEMBL13490598	0.78	CYP2D6 (0.51)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL13592728	0.77	PDE2A (0.46)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL30223549	0.77	PDE2A (0.44)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL13490665	0.76	CYP3A4 (0.50)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL17898213	0.74	CYP3A4 (0.53)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL13490514	0.74	CYP3A4 (0.58)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL28011532	0.74	PDE2A (0.47)	PDE2ACYP3A4CYP2D6CYP1A2CYP2C19
	SCHEMBL13490557	0.73	DRD2 (0.59)	DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.