Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.60 |
| ▸ | DRD4 | P21917 | 11/20 | 0.60 |
| ▸ | DRD3 | P35462 | 8/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171619 | 0.85 | PDE2A (0.55) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL13490449 | 0.83 | DRD2 (0.59) | DRD2DRD4DRD3ACHECCR3 | |
| SCHEMBL171521 | 0.83 | DRD2 (0.53) | DRD2DRD4DRD3ACHEMEN1 | |
| SCHEMBL13490557 | 0.82 | DRD2 (0.59) | DRD2DRD4DRD3ACHEMEN1 | |
| SCHEMBL13490669 | 0.80 | DRD2 (0.56) | DRD2DRD4DRD3ACHEMEN1 | |
| SCHEMBL21661933 | 0.78 | DRD2 (0.59) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL6195713 | 0.78 | DRD4 (0.59) | DRD2DRD4DRD3ACHEMEN1 | |
| Hydrochloric Acid SCHEMBL21642940 | 0.77 | DRD2 (0.58) | DRD2DRD4HTR1AKCNH2 | |
| SCHEMBL169363 | 0.77 | DRD2 (0.60) | DRD2DRD4DRD3ACHEMEN1 | |
| SCHEMBL17888476 | 0.77 | DRD2 (0.53) | DRD2DRD4HTR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029947-A1 | Pyridyltetrahydropyridines and Pyridylpiperidines, and Method of Manufacturing Them | FUJIFILM FINECHEMICALS CO., LTD | 2010-02-04 | — | — | US | disclosed |
| US-7632950-B2 | Pyridyltetrahydropyridines and pyridylpiperidines and method of manufacturing them | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2009-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029947-A1 | Pyridyltetrahydropyridines and Pyridylpiperidines, and Method of Manufacturing Them | QDPR, HRH4, HRH2 | DRD2 130/4885DRD4 112/4885DRD3 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.