Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121124 | 1.00 | TSHR (0.65) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL4200709 | 0.90 | TSHR (0.53) | TSHRSMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL16379302 | 0.90 | TSHR (0.53) | TSHRSMN1; SMN2KMT2AHPGDALDH1A1 | |
| SCHEMBL30423678 | 0.88 | FAAH (0.52) | TSHRKMT2AHPGDALDH1A1CYP2C9 | |
| SCHEMBL18300369 | 0.86 | TSHR (0.57) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL25842763 | 0.84 | TSHR (0.51) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL8224624 | 0.84 | SMN1; SMN2 (0.60) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL29006983 | 0.84 | TSHR (0.58) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL265567 | 0.84 | SMN1; SMN2 (0.60) | TSHRSMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL29232860 | 0.84 | TSHR (0.58) | TSHRSMN1; SMN2KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397358-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002102801-A1 | TROPANE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2002-12-27 | — | — | WO | disclosed |