SCHEMBL134932

SCHEMBL134932

CC(C)(C)OC(=O)Nc1ccc(Cc2ccc(N)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.67
MAPK14 Q16539 2/20 0.55
PPARG P37231 2/20 0.46
PPARA Q07869 1/20 0.46
MAPKAPK2 P49137 3/20 0.46
DRD2 P14416 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.46
MAP4K4 O95819 1/20 0.46
SAE1 Q9UBE0 1/20 0.45
UBA2 Q9UBT2 1/20 0.45
MAPT P10636 2/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
CASP6 P55212 1/20 0.44
GFER P55789 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132701 0.92 CYP17A1 (0.76) CYP17A1MAPK14PPARGPPARADRD2
SCHEMBL78108 0.91 MAPT (0.53) CYP17A1MAPKAPK2MAP4K4MAPTRAB9A
Hydrochloric Acid SCHEMBL28891842 0.89 MAPT (0.52) CYP17A1MAPKAPK2MAP4K4MAPTRAB9A
SCHEMBL1849865 0.87 CYP17A1 (0.52) CYP17A1MAPK14PPARGPPARASAE1
SCHEMBL14379115 0.86 CYP17A1 (0.68) CYP17A1MAPK14PPARGPPARADRD2
SCHEMBL10249437 0.86 CYP17A1 (0.68) CYP17A1MAPK14PPARGPPARADRD2
SCHEMBL26643063 0.86 PRMT1 (0.49) CYP17A1MAPKAPK2MAP4K4MAPTRAB9A
SCHEMBL3785153 0.86 CYP17A1 (0.59) CYP17A1MAPKAPK2MAP4K4MAPTRAB9A
SCHEMBL13654831 0.85 CYP17A1 (0.50) CYP17A1MAPK14PPARGPPARAMAPKAPK2
Methane SCHEMBL28036476 0.84 CYP17A1 (0.58) CYP17A1MAPKAPK2MAP4K4MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11681222-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2023-06-20 US disclosed
US-20220137508-A9 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2022-05-05 US disclosed
US-20210278764-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2021-09-09 US disclosed
US-20210200097-A1 TREATMENT LIQUID AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2021-07-01 US disclosed
US-11042094-B2 Treatment liquid and pattern forming method FUJIFILM CORPORATION (JP) 2021-06-22 US disclosed
US-11036133-B2 Fluorine-containing polymer, purification method, and radiation-sensitive resin composition JSR CORPORATION (JP) 2021-06-15 US disclosed
US-10962884-B2 Treatment liquid and pattern forming method FUJIFILM CORPORATION (JP) 2021-03-30 US disclosed
EP-2414896-B1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORP (JP) 2020-11-11 EP disclosed
US-20200166843-A1 PATTERN FORMING METHOD AND PROCESSING LIQUID JSR CORPORATION (JP) 2020-05-28 US disclosed
US-20200124961-A1 FLUORINE-CONTAINING POLYMER, PURIFICATION METHOD, AND RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2020-04-23 US disclosed
US-20020009668-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-24 US disclosed
EP-1164434-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed
EP-1164433-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed
EP-1162506-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-12 EP disclosed
US-20010023050-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2001-09-20 US disclosed
EP-1122605-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2001-08-08 EP disclosed
EP-1085379-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-03-21 EP disclosed
US-5334729-A Derivatives of 1,2-diaminocyclohexanetetraacetic acid ASSOCIATED UNIVERSITIES, INC. (US) 1994-08-02 US disclosed
US-5089663-A Chelating agents for labeling antibodies, antitumor agents ASSOCIATED UNIVERSITIES, INC. (US) 1992-02-18 US disclosed
US-5021571-A Rigid compound used in chelating stable radiometal labeled antibodies ASSOCIATED UNIVERSITIES, INC. (US) 1991-06-04 US disclosed