Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28891842 | 0.98 | MAPT (0.52) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| SCHEMBL3785153 | 0.95 | CYP17A1 (0.59) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| SCHEMBL26643063 | 0.95 | PRMT1 (0.49) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| Methane SCHEMBL28036476 | 0.93 | CYP17A1 (0.58) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| SCHEMBL8738157 | 0.92 | CYP17A1 (0.51) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| SCHEMBL21049533 | 0.92 | NAMPT (0.48) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| SCHEMBL134932 | 0.91 | CYP17A1 (0.67) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| SCHEMBL22461364 | 0.91 | POLB (0.67) | MAPTRAB9ACYP17A1TDP1NAMPT | |
| SCHEMBL13379490 | 0.91 | PTPN11 (0.54) | MAPTRAB9ACYP17A1MAP4K4TDP1 | |
| Aminobenzoic Acid SCHEMBL6627812 | 0.91 | CYP17A1 (0.50) | MAPTRAB9ACYP17A1MAP4K4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122148-A1 | HIGH-SELECTIVITY KCNQ4 POTASSIUM CHANNEL AGONIST, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-04-17 | — | — | US | claimed |
| CN-119505370-B | Method for preparing rubber additive by amino-functionalized graphene and rare earth compound | 内蒙古科技大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119505370-A | Method for preparing rubber additive by amino-functionalized graphene and rare earth compound | 内蒙古科技大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119264167-A | Amino functionalized carborane and preparation method and application thereof | 四川大学 | 2025-01-07 | — | — | CN | claimed |
| EP-4464690-A1 | HIGH-SELECTIVITY KCNQ4 POTASSIUM CHANNEL AGONIST, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2024-11-20 | — | — | EP | claimed |
| CN-118852008-A | Efficient organic I-type photosensitizer molecule as well as preparation method and application thereof | 西安交通大学 | 2024-10-29 | — | — | CN | claimed |
| CN-118108941-A | Preparation method and application of covalent organic framework nano material for pyroelectric power therapy | 华东理工大学 | 2024-05-31 | — | — | CN | claimed |
| CN-115010742-B | Blue light absorbent, silicon hydrogel cornea contact lens based on blue light absorbent and application of blue light absorbent | 苏州瑞尔康科技有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-115124519-B | Fluorescent reagent for detecting dimethyl chlorophosphate and preparation method thereof | 常州大学 | 2024-01-23 | — | — | CN | claimed |
| CN-115849656-B | Anaerobic ammonia oxidation denitrification method for anaerobic digestion biogas slurry of kitchen waste | 红菌生物(广东)有限公司 | 2023-09-01 | — | — | CN | claimed |
| CN-115124519-A | Fluorescent reagent for detecting dimethyl chlorophosphate and preparation method thereof | 常州大学 | 2022-09-30 | — | — | CN | claimed |
| CN-115010742-A | Blue light absorbent, silicon hydrogel corneal contact lens based on blue light absorbent and application of silicon hydrogel corneal contact lens | 苏州瑞尔康科技有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-112898193-B | Indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2022-08-05 | — | — | CN | claimed |
| CN-114149419-A | Oxadiazole drug molecule for medical nursing sterilization and disinfection and preparation method and application thereof | 河南科技大学第一附属医院 | 2022-03-08 | — | — | CN | claimed |
| CN-113461636-A | Benzothiazole-containing phenylalanine derivative and preparation method and application thereof | 山东大学 | 2021-10-01 | — | — | CN | claimed |
| CN-111053741-B | Oral multi-sensitive micelle prodrug based on beta-sitosterol and 5-ASA for treating inflammatory bowel disease | 江苏省中医院 | 2021-09-28 | — | — | CN | claimed |
| CN-111053741-A | Oral multi-sensitive micelle prodrug based on β -sitosterol and 5-ASA for treating inflammatory bowel disease | 江苏省中医院 | 2020-04-24 | — | — | CN | claimed |
| CN-103288761-B | The new method of one kind synthesis derovatives of 1,2,3,4 quinazoline 2,4 | 浙江华海药业股份有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-103288682-B | A kind of method of purification (4-aminophenyl) t-butyl carbamate of simplicity | 浙江华海药业股份有限公司 | 2016-06-22 | — | — | CN | claimed |
| CN-103288682-A | Simple and convenient method for purification of (4-aminophenyl) carbamic tert-butyl ester | ZHEJIANG HUAHAI PHARM CO LTD | 2013-09-11 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122148-A1 | HIGH-SELECTIVITY KCNQ4 POTASSIUM CHANNEL AGONIST, PREPARATION METHOD THEREFOR AND USE THEREOF | KCNQ4, KCNJ4, KCNA4 | MAPT 4430/4885RAB9A 3484/4885CYP17A1 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.