Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058071 | 0.83 | FLT3 (0.38) | IRAK4FLT3TYRO3MERTKGAS6 | |
| SCHEMBL12037650 | 0.82 | IRAK4 (0.59) | IRAK4 | |
| SCHEMBL13493704 | 0.77 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL12058354 | 0.76 | IRAK4 (0.37) | IRAK4 | |
| SCHEMBL12058119 | 0.75 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL13493532 | 0.71 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL12058252 | 0.71 | IRAK4 (0.36) | IRAK4 | |
| SCHEMBL13493549 | 0.69 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL13493555 | 0.67 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL13493415 | 0.66 | IRAK4 (0.58) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |