Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 16/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058059 | 0.85 | IRAK4 (0.50) | IRAK4 | |
| SCHEMBL13493549 | 0.82 | IRAK4 (0.48) | IRAK4CDK2KDM4EALDH1A1GAA | |
| SCHEMBL12058488 | 0.78 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL12037648 | 0.74 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL13493553 | 0.67 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL12058252 | 0.66 | IRAK4 (0.36) | IRAK4KDM4ELMNAMAPT | |
| SCHEMBL12058081 | 0.65 | IRAK4 (0.47) | IRAK4CDK2KDM4EALDH1A1GAA | |
| SCHEMBL13493532 | 0.65 | IRAK4 (0.42) | IRAK4MAPT | |
| SCHEMBL13493735 | 0.65 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL12058354 | 0.64 | IRAK4 (0.37) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |