Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058343 | 0.88 | IRAK4 (0.40) | IRAK4CD38VCPKDM4EATM | |
| SCHEMBL12038207 | 0.86 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL12058492 | 0.86 | IRAK4 (0.30) | IRAK4 | |
| SCHEMBL12057848 | 0.86 | IRAK4 (0.34) | IRAK4CD38VCPKDM4EATM | |
| SCHEMBL13493633 | 0.82 | IRAK4 (0.37) | IRAK4VCPKDM4EMAPK1 | |
| SCHEMBL12038597 | 0.82 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL12038205 | 0.80 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL12058185 | 0.80 | VCP (0.34) | IRAK4CD38VCPKDM4EATM | |
| SCHEMBL12038204 | 0.80 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL12058302 | 0.79 | CCNT1 (0.36) | IRAK4VCPKDM4EATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |