Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12058343 | 0.94 | IRAK4 (0.40) | IRAK4KDM4EVCP | |
| SCHEMBL12038205 | 0.91 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL13493420 | 0.87 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL12058185 | 0.85 | VCP (0.34) | IRAK4KDM4EMAPK1VCP | |
| SCHEMBL12038203 | 0.84 | IRAK4 (0.47) | IRAK4 | |
| SCHEMBL12038207 | 0.84 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL13493573 | 0.82 | IRAK4 (0.36) | IRAK4KDM4EMAPK1VCP | |
| SCHEMBL12038198 | 0.80 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL12038597 | 0.80 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL12057848 | 0.79 | IRAK4 (0.34) | IRAK4KDM4EMAPK1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |