Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 18/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070353 | 0.87 | DYRK1A (0.73) | DYRK1APLA2G2AHTR2AHTR2C | |
| SCHEMBL13494641 | 0.86 | DYRK1A (0.66) | DYRK1AHTR2AHTR2C | |
| SCHEMBL27921175 | 0.78 | DYRK1A (0.67) | DYRK1AHTR2AHTR2C | |
| SCHEMBL27939720 | 0.75 | DYRK1A (0.50) | DYRK1AHTR2AHTR2C | |
| SCHEMBL27899833 | 0.74 | DYRK1A (0.55) | DYRK1A | |
| SCHEMBL8852076 | 0.74 | DYRK1A (0.70) | DYRK1A | |
| SCHEMBL30939988 | 0.73 | DYRK1A (0.71) | DYRK1AHTR2AHTR2C | |
| SCHEMBL16123659 | 0.73 | DYRK1A (0.71) | DYRK1AHTR2AHTR2C | |
| SCHEMBL12070349 | 0.73 | DYRK1A (1.00) | DYRK1AHTR2AHTR2C | |
| SCHEMBL12288128 | 0.72 | HASPIN (0.74) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015636-A1 | BETA-CARBOLIN-DERIVATES AS SUBSTRATES FOR AN ENZYME | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2010-02-11 | — | — | WO | disclosed |