Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 12/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234392 | 1.00 | ADK (0.50) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3234421 | 1.00 | ADK (0.50) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3226243 | 0.93 | ADK (0.47) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3226222 | 0.93 | ADK (0.47) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3229936 | 0.90 | ADK (0.44) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3234007 | 0.90 | ADK (0.44) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3229959 | 0.90 | ADK (0.44) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3233982 | 0.90 | ADK (0.44) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL3224465 | 0.88 | ADK (0.43) | ADKNPC1GALR3S1PR4ALDH1A1 | |
| SCHEMBL13494168 | 0.88 | ADK (0.43) | ADKNPC1GALR3S1PR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015643-A1 | NEW ANTIVIRAL MODIFIED NUCLEOSIDES | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | disclosed |