SCHEMBL3234392

SCHEMBL3234392

C#C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cc(C(N)=O)c2c(N)ncnc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 12/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ GALR3 O60755 1/20 0.50
▸ S1PR4 O95977 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ S1PR1 P21453 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ PAX8 Q06710 1/20 0.50
▸ DOT1L Q8TEK3 3/20 0.48
▸ ADORA2A P29274 1/20 0.45
▸ CDK1 P06493 2/20 0.42
▸ CDK2 P24941 2/20 0.42
▸ CCNB1 P14635 1/20 0.42
▸ CCNA2 P20248 1/20 0.42
▸ CCNA1 P78396 1/20 0.42
▸ HIF1A Q16665 1/20 0.41
▸ HSPA8 P11142 1/20 0.40
▸ CDK5 Q00535 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3234421 1.00 ADK (0.50) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL13495010 1.00 ADK (0.50) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL3226243 0.93 ADK (0.47) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL3226222 0.93 ADK (0.47) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL3229936 0.90 ADK (0.44) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL3234007 0.90 ADK (0.44) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL3229959 0.90 ADK (0.44) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL3233982 0.90 ADK (0.44) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL3224465 0.88 ADK (0.43) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL13494168 0.88 ADK (0.43) ADKNPC1GALR3S1PR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12083185-B2 Small polymeric carriers for delivery of agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-09-10 — — US claimed
US-12466849-B2 Anti-viral and anti-tumoral compounds YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-11-11 — — US disclosed
US-20250281574-A1 COMPOSITIONS AND METHODS FOR TREATING COMPLICATIONS OF VIRAL INFECTIONS AND OTHER RESPIRATORY DISORDERS XEQUEL BIO INC (US) 2025-09-11 — — US disclosed
US-20250161334-A1 Method Of Treating, Reducing, Or Alleviating A Medical Condition In A Patient PEYMAN GHOLAM A (US) 2025-05-22 — — US disclosed
US-20250057975-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2025-02-20 — — US disclosed
US-12226478-B2 Method of treating, reducing, or alleviating a medical condition in a patient PEYMAN GHOLAM A (US) 2025-02-18 — — US disclosed
US-12083185-B2 Small polymeric carriers for delivery of agents University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-09-10 — — US disclosed
WO-2023212446-A1 COMPOSITIONS AND METHODS FOR TREATING COMPLICATIONS OF VIRAL INFECTIONS AND OTHER RESPIRATORY DISORDERS XEQUEL BIO, INC. (US) 2023-11-02 — — WO disclosed
US-20230338520-A1 Method Of Treating, Reducing, Or Alleviating A Medical Condition In A Patient PEYMAN GHOLAM A (US) 2023-10-26 — — US disclosed
EP-4228656-A2 ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS Yeda Research and Development Co. Ltd (IL) 2023-08-23 — — EP disclosed
WO-2021209425-A9 ALKYNYL NUCLEOSIDE ANALOGS FOR TREATMENT OF HEPATITIS E Janssen Pharmaceuticals, Inc. (US) 2022-12-22 — — WO disclosed
US-20220202933-A1 Method Of Treating, Reducing, Or Alleviating A Medical Condition In A Patient PEYMAN GHOLAM A (US) 2022-06-30 — — US disclosed
WO-2021209425-A1 ALKYNYL NUCLEOSIDE ANALOGS FOR TREATMENT OF HEPATITIS E Janssen Sciences Ireland Unlimited Company (IE) 2021-10-21 — — WO disclosed
US-20100144655-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-06-10 — — US disclosed
US-20100144655-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-06-10 — — US disclosed
US-20100144655-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-06-10 — — US disclosed
WO-2010015637-A1 NEW ANTIVIRAL MODIFIED NUCLEOSIDES NOVARTIS AG (CH) 2010-02-11 — — WO disclosed
WO-2010015643-A1 NEW ANTIVIRAL MODIFIED NUCLEOSIDES NOVARTIS AG (CH) 2010-02-11 — — WO disclosed
WO-2010015637-A1 NEW ANTIVIRAL MODIFIED NUCLEOSIDES NOVARTIS AG (CH) 2010-02-11 — — WO disclosed
WO-2010015643-A1 NEW ANTIVIRAL MODIFIED NUCLEOSIDES NOVARTIS AG (CH) 2010-02-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466849-B2 Anti-viral and anti-tumoral compounds EIF2AK2, NSUN2, SARS1 ADK 1513/4885NPC1 1602/4885GALR3 2657/4885
US-20250057975-A1 SMALL POLYMERIC CARRIERS FOR DELIVERY OF AGENTS CD44, PGF, SLC46A1 ADK 4798/4885NPC1 781/4885GALR3 1331/4885
US-12083185-B2 Small polymeric carriers for delivery of agents CD44, PGF, SLC46A1 ADK 4798/4885NPC1 781/4885GALR3 1331/4885
US-20100144655-A1 ORGANIC COMPOUNDS OAT, MAVS, HAVCR2 ADK 3634/4885NPC1 88/4885GALR3 3128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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