Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174610 | 0.79 | MEN1 (0.56) | KCNN4ALDH1A1TP53MAPTMEN1 | |
| SCHEMBL3262792 | 0.77 | MAPK1 (0.53) | P2RY1ALDH1A1MAPTPOLB | |
| SCHEMBL3260273 | 0.77 | CACNA1B (0.42) | KCNN4PLK1ALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL3263163 | 0.77 | POLB (0.46) | PLK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1826994 | 0.76 | CYP1A2 (0.56) | KCNN4ALDH1A1TP53MAPTMEN1 | |
| SCHEMBL15442119 | 0.76 | KCNN4 (0.44) | P2RY1KCNN4ALDH1A1TP53MAPT | |
| SCHEMBL3263951 | 0.72 | KDM5A (0.43) | ALDH1A1MAPTMEN1KMT2AUSP2 | |
| SCHEMBL3264182 | 0.72 | KCNN4 (0.39) | KCNN4PLK1ALDH1A1MAPTSLC16A3 | |
| SCHEMBL3390240 | 0.72 | PLK1 (0.39) | KCNN4PLK1ALDH1A1MAPTSLC16A3 | |
| SCHEMBL15428768 | 0.70 | MAPK14 (0.44) | P2RY1ALDH1A1MAPTMEN1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |