Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264182 | 0.84 | KCNN4 (0.39) | PLK1KCNN4ALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL3261663 | 0.79 | NPSR1 (0.45) | ALDH1A1DHODHMAPTHPGDKDM4E | |
| SCHEMBL3261819 | 0.75 | KMT2A (0.44) | PLK1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL13495136 | 0.72 | P2RY1 (0.44) | PLK1KCNN4ALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL3260273 | 0.72 | CACNA1B (0.42) | PLK1KCNN4ALDH1A1SLC16A3SLC16A1 | |
| SCHEMBL3264376 | 0.70 | CYP1A2 (0.40) | HTT | |
| SCHEMBL15443100 | 0.70 | KCNN4 (0.47) | PLK1KCNN4ALDH1A1MAPTHPGD | |
| SCHEMBL11560641 | 0.69 | ABHD16A (0.46) | SLC16A3SLC16A1NR1I2MGLL | |
| SCHEMBL3264346 | 0.68 | KDM4E (0.43) | ALDH1A1MAPTHPGDKDM4ESMO | |
| SCHEMBL15442337 | 0.68 | SMO (0.47) | PLK1KCNN4ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |