SCHEMBL13495256

CON(C)C(=O)c1ccc(-c2c3nc(c(-c4ccc(C(=O)N(C)OC)cc4)c4ccc([nH]4)c(-c4ccc(C(=O)N(C)OC)cc4)c4nc(c(-c5ccc(C(=O)N(C)OC)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.63

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	TOP1	P11387	4/20	0.63

▸	CYCS	P99999	4/20	0.60

▸	ABCG2	Q9UNQ0	1/20	0.55

▸	TERT	O14746	5/20	0.49

▸	ENPP2	Q13822	1/20	0.49

▸	MLYCD	O95822	1/20	0.41

▸	HPGDS	O60760	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3892703	0.81	ABCG2 (0.71)	TOP1CYCSABCG2TERTENPP2
SCHEMBL29583274	0.81	ABCG2 (0.71)	TOP1CYCSABCG2TERTENPP2
SCHEMBL13495254	0.80	TOP1 (0.63)	TOP1CYCSABCG2TERTENPP2
SCHEMBL28498163	0.80	ABCG2 (0.70)	TOP1CYCSABCG2TERTENPP2
SCHEMBL30872331	0.80	ABCG2 (0.70)	TOP1CYCSABCG2TERTENPP2
SCHEMBL28491269	0.80	ABCG2 (0.70)	TOP1CYCSABCG2TERTENPP2
SCHEMBL28463987	0.80	ABCG2 (0.70)	TOP1CYCSABCG2TERTENPP2
SCHEMBL28131499	0.80	ABCG2 (0.70)	TOP1CYCSABCG2TERTENPP2
SCHEMBL5012384	0.80	TOP1 (0.60)	TOP1CYCSABCG2TERTENPP2
Hydrochloric Acid SCHEMBL28130818	0.78	ABCG2 (0.68)	TOP1CYCSABCG2TERTENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20100035013-A1	OPTICAL RECORDING MEDIUM	MITSUBISHI KAGAKU MEDIA CO., LTD. (JP)	2010-02-11	—	—	US	disclosed
US-20100035013-A1	OPTICAL RECORDING MEDIUM	MITSUBISHI KAGAKU MEDIA CO., LTD. (JP)	2010-02-11	—	—	US	disclosed