SCHEMBL13495341

SCHEMBL13495341

CON1C(=O)c2cccc3cc(C)cc(c23)C1=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
KDM4E B2RXH2 6/20 0.50
HPGD P15428 5/20 0.50
TDP1 Q9NUW8 1/20 0.48
HSD17B10 Q99714 3/20 0.47
LMNA P02545 1/20 0.47
MPO P05164 1/20 0.46
KMT2A Q03164 5/20 0.46
CYP1B1 Q16678 2/20 0.46
MEN1 O00255 4/20 0.44
MAPT P10636 2/20 0.43
ERCC1 P07992 1/20 0.43
FEN1 P39748 1/20 0.43
ERCC4 Q92889 1/20 0.43
HTT P42858 1/20 0.43
RAD52 P43351 1/20 0.43
CLTC Q00610 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10040988 0.86 TDP1 (0.60) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL13495351 0.86 TDP1 (0.47) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL13495348 0.84 RAD52 (0.60) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL13495362 0.84 BRD1 (0.52) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL12672646 0.81 ALDH1A1 (0.51) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL13496099 0.81 TDP1 (0.46) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL7703367 0.80 ERCC1 (0.70) ALDH1A1KDM4EHPGDTDP1HSD17B10
SCHEMBL13495360 0.80 FTO (0.61) ALDH1A1KDM4EHPGDTDP1LMNA
SCHEMBL7703774 0.79 TDP1 (0.50) ALDH1A1KDM4EHPGDTDP1MPO
SCHEMBL19985736 0.78 KDM4E (0.85) ALDH1A1KDM4EHPGDLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329377-B2 Imide compound and chemically amplified resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-11 US disclosed
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028807-A1 Imide Compound and Chemically Amplified Resist Composition Containing The Same IGF1R, CCNA1, MYC ALDH1A1 386/4885KDM4E 1539/4885HPGD 4030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.