Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495742 | 0.87 | HSD17B1 (0.50) | HSD17B1HSD17B2ADORA3ALDH1A1MEN1 | |
| SCHEMBL9400208 | 0.82 | HSD17B1 (0.77) | HSD17B1HSD17B2ADORA3ALDH1A1MEN1 | |
| SCHEMBL11210548 | 0.78 | MEN1 (0.58) | HSD17B1HSD17B2ALDH1A1MEN1KMT2A | |
| SCHEMBL16371520 | 0.76 | NPC1 (0.51) | PIK3CAPIK3CGCA1CA2CA9 | |
| SCHEMBL13495708 | 0.75 | ALDH1A1 (0.51) | HSD17B1HSD17B2ADORA3ALDH1A1MEN1 | |
| SCHEMBL26028768 | 0.75 | HSD17B1 (0.66) | HSD17B1HSD17B2ADORA3ALDH1A1MEN1 | |
| SCHEMBL30665901 | 0.74 | MEN1 (0.50) | HSD17B1HSD17B2ALDH1A1MEN1KMT2A | |
| SCHEMBL11638321 | 0.74 | MEN1 (0.54) | HSD17B1HSD17B2ALDH1A1MEN1KMT2A | |
| SCHEMBL26654625 | 0.74 | MEN1 (0.50) | HSD17B1HSD17B2ALDH1A1MEN1KMT2A | |
| SCHEMBL13495706 | 0.74 | HSD17B1 (0.51) | HSD17B1HSD17B2ADORA3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012745-A2 | BENZIMIDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |