Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Acrylamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.42 |
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylamide SCHEMBL28603972 | 1.00 | TSHR (0.48) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL3636541 | 0.98 | TSHR (0.50) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL28232213 | 0.96 | TSHR (0.44) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL21630022 | 0.96 | TSHR (0.48) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL28403516 | 0.96 | TSHR (0.48) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL18550624 | 0.96 | TSHR (0.48) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL27538064 | 0.94 | TSHR (0.46) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL28232212 | 0.94 | TSHR (0.46) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL8504113 | 0.91 | TDP1 (0.43) | TSHRALDH1A1FGFR4CHRM5CHRM1 | |
| Acrylamide SCHEMBL27794839 | 0.90 | TSHR (0.42) | TSHRALDH1A1FGFR4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028892-A | Composition for conditioning hair | 莱雅公司 | 2026-05-12 | — | — | CN | claimed |
| CN-120199787-A | Silicon-carbon composite material and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2025-06-24 | — | — | CN | claimed |
| CN-115969726-B | Multi-effect composition, shampoo and preparation method thereof | 广州市芙缇化妆品有限公司 | 2025-06-24 | — | — | CN | claimed |
| US-12331147-B2 | Polymer and its preparation method | SNF GROUP (FR) | 2025-06-17 | — | — | US | claimed |
| CN-120082002-A | Low-surface-energy antibacterial resin material, preparation method and marine antifouling paint | 中国人民武装警察部队士官学校 | 2025-06-03 | — | — | CN | claimed |
| US-20250171576-A1 | NEW POLYMER AND ITS PREPARATION METHOD | SNF GROUP (FR) | 2025-05-29 | — | — | US | claimed |
| CN-119980753-A | Papermaking method for improving paper strength | 瑞辰星生物技术（广州）有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119837841-A | Glaucocalyxin A nano transdermal delivery system for skin anti-inflammation and preparation method thereof | 上海交通大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119798311-A | Anti-mud monomer and preparation method thereof, and anti-mud water reducer and preparation method thereof | 科之杰新材料集团有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-116003696-B | Polyurethane-cationic polymer emulsion with interpenetrating network structure, preparation method and application thereof in personal care field | 万华化学集团股份有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-1081705-C | Method for making paper | HYMO CORP (JP) | 2002-03-27 | — | — | CN | claimed |
| CN-1322876-A | Prepn of water soluble quarternary copolymer softener | GUANGDONG AIQIMEI SCIENCE & TE (CN) | 2001-11-21 | — | — | CN | claimed |
| EP-0877120-B1 | PAPERMAKING PROCESS | HYMO CORP (JP) | 2000-03-22 | — | — | EP | claimed |
| CN-1050281-C | Agent for treatment of hair | HENKEL KGAA (DE) | 2000-03-15 | — | — | CN | claimed |
| CN-1205756-A | Papermaking process | HYMO CORP (JP) | 1999-01-20 | — | — | CN | claimed |
| EP-0877120-A1 | PAPERMAKING PROCESS | HYMO CORPORATION (JP) | 1998-11-11 | — | — | EP | claimed |
| US-5776362-A | WATER SOLUBILITY; STORAGE STABILITY | KURITA WATER INDUSTRIES LTD. (JP) | 1998-07-07 | — | — | US | claimed |
| US-5512277-A | APPLYING CATIONIC POLYMER HAVING SALT FORMING GROUP TO SKIN, PEELING OFF AFTER DRYING | KAO CORPORATION (JP) | 1996-04-30 | — | — | US | claimed |
| US-5326819-A | Water absorbent polymer keeping absorbed water therein in the form of independent grains | OOSAKA YUUKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-07-05 | — | — | US | claimed |
| US-5200086-A | Treating wastes containing fatty acid esters or phosphoric acid w/a cationic polymer & a water insoluble filter aid, mixing, forming a coacervated slurry, removing esters of phosphoric acid by disposing of slurry phase & discharging | NALCO CHEMICAL COMPANY (US) | 1993-04-06 | — | — | US | claimed |