Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 12/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768863 | 0.92 | PDK2 (0.45) | PDK2APEX1CES2CES1MMP2 | |
| SCHEMBL3557701 | 0.87 | THRA (0.47) | PDK2APEX1CES2CES1MMP2 | |
| SCHEMBL4821046 | 0.86 | APEX1 (0.47) | PDK2APEX1 | |
| SCHEMBL28776646 | 0.86 | PDK2 (0.51) | PDK2APEX1MMP2MMP9MMP8 | |
| SCHEMBL28871391 | 0.86 | PDK2 (0.51) | PDK2APEX1MMP2MMP9MMP8 | |
| SCHEMBL25070269 | 0.86 | APEX1 (0.47) | PDK2APEX1 | |
| SCHEMBL4822886 | 0.85 | PDK2 (0.43) | PDK2APEX1MMP2MMP9MMP8 | |
| SCHEMBL15159198 | 0.83 | PDK2 (0.42) | PDK2APEX1MMP2MMP9MMP8 | |
| SCHEMBL13538673 | 0.82 | PDK2 (0.38) | PDK2APEX1 | |
| SCHEMBL3554733 | 0.82 | THRB (0.47) | PDK2APEX1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2154213-A1 | Ink-jet ink composition, and ink-jet recording method | Fujifilm Corporation (JP) | 2010-02-17 | — | — | EP | disclosed |