Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRYAB | P02511 | 5/20 | 0.80 |
| ▸ | CRYAA | P02489 | 1/20 | 0.80 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | PTGES | O14684 | 2/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.55 |
| ▸ | FNTB | P49356 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527661 | 1.00 | CRYAB (0.80) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL568417 | 1.00 | CRYAB (0.80) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL19198688 | 1.00 | CRYAB (0.80) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL288307 | 1.00 | CRYAB (0.80) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL288306 | 1.00 | CRYAB (0.80) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL6130528 | 1.00 | CRYAB (0.80) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| Lanosterol SCHEMBL3658283 | 0.92 | CRYAB (0.89) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL26237645 | 0.92 | CRYAB (0.80) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL25412532 | 0.90 | CRYAB (0.74) | CRYABCRYAAUSP2ALDH1A1CYP3A4 | |
| SCHEMBL25412530 | 0.90 | CRYAB (0.74) | CRYABCRYAAUSP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910421-B1 | COMPOSITIONS AND METHODS FOR METABOLIC SELECTION OF TRANSFECTED CELLS | BIOFACTURA INC (US) | 2019-03-13 | — | — | EP | disclosed |
| US-8076102-B2 | Compositions and methods for metabolic selection of transfected cells | BIOFACTURA, INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20100028940-A1 | Compositions and Methods for Metabolic Selection of Transfected Cells | BIOFACTURA, INC. (US) | 2010-02-04 | — | — | US | disclosed |