Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 8/20 | 0.67 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.61 |
| ▸ | NAT1 | P18440 | 3/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | MAX | P61244 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499558 | 0.89 | PTP4A3 (0.71) | PTP4A3CISD1NAT1CRHBPCRHR2 | |
| SCHEMBL13499579 | 0.86 | PTP4A3 (0.67) | PTP4A3NAT1CRHBPCRHR2PIM1 | |
| SCHEMBL13499560 | 0.82 | PTP4A3 (0.65) | PTP4A3CISD1NAT1CRHBPCRHR2 | |
| SCHEMBL14464046 | 0.81 | PTP4A3 (0.71) | PTP4A3CISD1NAT1CRHBPCRHR2 | |
| SCHEMBL14464056 | 0.81 | PTP4A3 (1.00) | PTP4A3CISD1NAT1CRHBPCRHR2 | |
| SCHEMBL14463959 | 0.81 | PTP4A3 (0.71) | PTP4A3CISD1NAT1CRHBPCRHR2 | |
| SCHEMBL12892069 | 0.77 | PTP4A3 (0.63) | PTP4A3CISD1NAT1CRHBPCRHR2 | |
| SCHEMBL13499577 | 0.77 | NAT1 (0.64) | PTP4A3NAT1CRHBPCRHR2PIM1 | |
| SCHEMBL10090230 | 0.77 | PTP4A3 (0.71) | PTP4A3CISD1NAT1CA2 | |
| SCHEMBL2065276 | 0.77 | PTP4A3 (0.71) | PTP4A3CISD1NAT1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| WO-2006071255-A9 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2007-02-15 | — | — | WO | disclosed |