Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 5/20 | 1.00 |
| ▸ | NAT1 | P18440 | 2/20 | 0.66 |
| ▸ | CISD1 | Q9NZ45 | 6/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | MYC | P01106 | 1/20 | 0.60 |
| ▸ | MAX | P61244 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.53 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.53 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102943 | 0.86 | PTP4A3 (0.75) | PTP4A3NAT1CISD1GSK3BMYC | |
| SCHEMBL8174040 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1GSK3BMYC | |
| SCHEMBL14464046 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1CRHBPCRHR2 | |
| SCHEMBL14464055 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1GSK3BMYC | |
| SCHEMBL13616173 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1GSK3BMYC | |
| SCHEMBL13499558 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1MYCMAX | |
| SCHEMBL3405858 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1GSK3BMYC | |
| SCHEMBL18102858 | 0.83 | PTP4A3 (0.75) | PTP4A3NAT1CISD1GSK3BMYC | |
| SCHEMBL8174037 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1GSK3BMYC | |
| SCHEMBL14463959 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081091-A1 | RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-07-19 | — | — | WO | disclosed |