Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 5/20 | 0.71 |
| ▸ | NAT1 | P18440 | 4/20 | 0.66 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499558 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1CRHBPCRHR2 | |
| SCHEMBL14463959 | 0.83 | PTP4A3 (0.71) | PTP4A3NAT1CISD1MEN1MAPT | |
| SCHEMBL14899471 | 0.83 | PTP4A3 (0.75) | PTP4A3NAT1CISD1MEN1MAPT | |
| SCHEMBL14464056 | 0.83 | PTP4A3 (1.00) | PTP4A3NAT1CISD1CRHBPCRHR2 | |
| SCHEMBL12892067 | 0.82 | PTP4A3 (0.65) | PTP4A3NAT1CISD1MEN1MAPT | |
| SCHEMBL14464141 | 0.81 | NAT1 (0.63) | NAT1CISD1MEN1MAPTKMT2A | |
| SCHEMBL4803625 | 0.81 | CA2 (0.73) | NAT1CISD1MEN1MAPTKMT2A | |
| SCHEMBL4803620 | 0.81 | CA2 (0.73) | NAT1CISD1MEN1MAPTKMT2A | |
| SCHEMBL13499559 | 0.81 | PTP4A3 (0.67) | PTP4A3NAT1CISD1CRHBPCRHR2 | |
| SCHEMBL10090200 | 0.80 | PTP4A3 (0.70) | PTP4A3NAT1CISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081091-A1 | RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-07-19 | — | — | WO | disclosed |