Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19123358 | 0.84 | SLC6A1 (0.38) | USP30SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL13503183 | 0.83 | SLC6A1 (0.38) | USP30SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL728213 | 0.74 | — | — | |
| SCHEMBL10059951 | 0.74 | — | — | |
| SCHEMBL10060804 | 0.74 | — | — | |
| SCHEMBL13452891 | 0.73 | SHBG (0.37) | — | |
| SCHEMBL30150910 | 0.73 | SLC6A1 (0.39) | USP30SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL10562710 | 0.73 | SLC6A1 (0.39) | USP30SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL25960704 | 0.73 | SLC6A1 (0.39) | USP30SLC6A1GABRA5GABRB2SLC6A12 | |
| SCHEMBL12339289 | 0.73 | SLC6A1 (0.36) | USP30SLC6A1GABRA5GABRB2SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7667052-B2 | Bioactive substance | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-02-23 | — | — | US | disclosed |