Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.56 |
| ▸ | SELP | P16109 | 5/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.49 |
| ▸ | IKBKB | O14920 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.49 |
| ▸ | PAK4 | O96013 | 2/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | INSR | P06213 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379898 | 0.93 | CNR2 (0.64) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL3380654 | 0.91 | CNR2 (0.64) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL13503393 | 0.89 | CNR2 (0.57) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL3379695 | 0.85 | CNR2 (0.75) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL29510131 | 0.85 | CNR2 (0.75) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL3382659 | 0.85 | CNR2 (0.75) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL3377491 | 0.85 | CNR2 (0.75) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL3383682 | 0.83 | CNR2 (0.75) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL3377492 | 0.82 | CNR2 (0.66) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL14319080 | 0.82 | CNR2 (0.55) | CNR2CYP2C19CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041654-A1 | Pyrimidine Derivatives And Their Use As CB2 Modulators | EATHERTON ANDREW JOHN | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041654-A1 | Pyrimidine Derivatives And Their Use As CB2 Modulators | CNR2, CNR1, P2RY2 | CNR2 1/4885CYP2C19 641/4885CYP2C9 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.