SCHEMBL3379695

SCHEMBL3379695

O=C(NC1CCCC1)c1cnc(Nc2cccc(Cl)c2)nc1C(F)(F)F

nearest known ligand 0.75

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.75
CYP2C9 P11712 8/20 0.75
CYP2C19 P33261 8/20 0.75
CYP3A4 P08684 7/20 0.75
CYP1A2 P05177 6/20 0.75
CYP2D6 P10635 5/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510131 1.00 CNR2 (0.75) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL3377491 0.99 CNR2 (0.75) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL3382659 0.99 CNR2 (0.75) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL3383682 0.98 CNR2 (0.75) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL3378974 0.96 CNR2 (0.74) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL13503357 0.92 CNR2 (0.68) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL13503327 0.92 CNR2 (0.76) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL3379898 0.90 CNR2 (0.64) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL3379009 0.89 CNR2 (0.64) CNR2CYP2C9CYP2C19CYP3A4CYP1A2
SCHEMBL3380529 0.88 CNR2 (0.63) CNR2CYP2C9CYP2C19CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1878725-B1 Pyrimidine derivatives and their use as CB2 modulators GLAXO GROUP LTD (GB) 2010-11-24 EP claimed
CN-100351239-C Pyrimidine derivatives and their use as CB2 modulators GLAXO GROUP LTD (GB) 2007-11-28 CN claimed
US-12303487-B2 N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions SPOKE SCIENCES, INC. (US) 2025-05-20 US disclosed
US-20250152509-A1 PARTICLES, AQUEOUS DISPERSIONS, AND LIQUID COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS SPOKE SCIENCES, INC. (US) 2025-05-15 US disclosed
US-20240261303-A1 PARTICLES, AQUEOUS DISPERSIONS, AND COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS SPOKE SCIENCES, INC. 2024-08-08 US disclosed
US-20240009208-A1 STABILIZATION OF CANNABINOIDS WITHIN SOLID DOSAGE FORMS RECEPTOR HOLDINGS, INC. (US) 2024-01-11 US disclosed
WO-2023201303-A2 SYSTEMS AND METHODS TO AUTOMATICALLY ADMINISTER A PSYCHOACTIVE SUBSTANCE TO AN AIRWAY OF A USER BASED ON A DETECTED EVENT OR CONDITION Green Sky Creations, LLC (US) 2023-10-19 WO disclosed
US-20230293479-A1 MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS RECEPTOR HOLDINGS, INC. (US) 2023-09-21 US disclosed
WO-2023102134-A2 PARTICLES, AQUEOUS DISPERSIONS, AND LIQUID COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS SPOKE SCIENCES, INC. (US) 2023-06-08 WO disclosed
US-11670410-B1 Systems and methods to automatically administer a psychoactive substance to an airway of a user based on a detected event or condition Green Sky Creations LLC (US) 2023-06-06 US disclosed
US-20230087756-A1 SYSTEMS AND METHODS FOR GENERATING HOMOGENOUS MIXTURES OF BREWED BEVERAGES AND ACTIVE INGREDIENTS RECEPTOR HOLDINGS, INC. (US) 2023-03-23 US disclosed
EP-1878725-A2 Pyrimidine derivatives and their use as CB2 modulators GLAXO GROUP LIMITED (GB) 2008-01-16 EP disclosed
EP-1878725-A2 Pyrimidine derivatives and their use as CB2 modulators GLAXO GROUP LIMITED (GB) 2008-01-16 EP disclosed
CN-100351239-C Pyrimidine derivatives and their use as CB2 modulators GLAXO GROUP LTD (GB) 2007-11-28 CN disclosed
US-20060293354-A1 Pyrimidine derivatives and their use as CB2 modulators GLAXO GROUP LIMITED (GB) 2006-12-28 US disclosed
EP-1732561-A1 COMBINATION OF CB2 MODULATORS AND PDE4 INHIBITORS FOR USE IN MEDICINE GLAXO GROUP LIMITED (GB) 2006-12-20 EP disclosed
CN-1688552-A Pyrimidine derivatives and their use as CB2 modulators GLAXO GROUP LTD (GB) 2005-10-26 CN disclosed
WO-2005074939-A1 COMBINATION OF CB2 MODULATORS AND PDE4 INHIBITORS FOR USE IN MEDICINE GLAXO GROUP LIMITED (GB) 2005-08-18 WO disclosed
EP-1539712-A1 PYRIMIDINE DERIVATIVES AND THEIR USE AS CB2 MODULATORS GLAXO GROUP LIMITED (GB) 2005-06-15 EP disclosed
WO-2004018433-A1 PYRIMIDINE DERIVATIVES AND THEIR USE AS CB2 MODULATORS GLAXO GROUP LIMITED (GB) 2004-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293479-A1 MEDICINAL COMPOUNDS AND NUTRITIONAL SUPPLEMENTS GPR18, SLC1A5, CNR2 CNR2 3/4885CYP2C9 340/4885CYP2C19 341/4885
US-20250152509-A1 PARTICLES, AQUEOUS DISPERSIONS, AND LIQUID COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS NAPEPLD, CNR1, CNR2 CNR2 3/4885CYP2C9 666/4885CYP2C19 652/4885
US-12303487-B2 N-acylated fatty amino acids to reduce absorption variability in cannabinoid based compositions FAAH, CNR2, FABP2 CNR2 2/4885CYP2C9 132/4885CYP2C19 222/4885
US-20240009208-A1 STABILIZATION OF CANNABINOIDS WITHIN SOLID DOSAGE FORMS DGKZ, DSP, DMPK CNR2 6/4885CYP2C9 3066/4885CYP2C19 1915/4885
US-20060293354-A1 Pyrimidine derivatives and their use as CB2 modulators CNR2, CNR1, P2RX3 CNR2 1/4885CYP2C9 1187/4885CYP2C19 810/4885
US-20240261303-A1 PARTICLES, AQUEOUS DISPERSIONS, AND COMPOSITIONS HAVING HIGH LIPOPHILIC COMPONENT CONCENTRATIONS AND HIGH LIPOPHILIC COMPONENT TO SURFACTANT RATIOS LIPA, PLIN3, LPL CNR2 1444/4885CYP2C9 1527/4885CYP2C19 1284/4885
US-20230087756-A1 SYSTEMS AND METHODS FOR GENERATING HOMOGENOUS MIXTURES OF BREWED BEVERAGES AND ACTIVE INGREDIENTS CEL, ABHD6, LCT CNR2 2663/4885CYP2C9 1678/4885CYP2C19 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.