Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10471573 | 0.77 | ALDH1A1 (0.42) | TSHR | |
| SCHEMBL27692607 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL27534244 | 0.72 | TSHR (0.32) | TSHR | |
| SCHEMBL1457226 | 0.71 | — | — | |
| SCHEMBL3679168 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL27376630 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL10333609 | 0.69 | TSHR (0.33) | TSHR | |
| SCHEMBL11575966 | 0.67 | — | — | |
| SCHEMBL5861177 | 0.67 | — | — | |
| SCHEMBL10596552 | 0.63 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702032-B1 | PROCESS FOR THE PRODUCTION OF 4-CHLOROACETOACETYL CHLORIDE, 4-CHLOROACETOACETIC ACID ESTERS, AMIDES AND IMIDES | LONZA AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-9227905-B2 | Process for the production of 4-chloroacetoacetyl chloride, 4-chloroacetoacetic acid esters, amides and imides | LONZA LTD. (CH) | 2016-01-05 | — | — | US | disclosed |
| EP-2702032-A1 | PROCESS FOR THE PRODUCTION OF 4-CHLOROACETOACETYL CHLORIDE, 4-CHLOROACETOACETIC ACID ESTERS, AMIDES AND IMIDES | Lonza Ltd (CH) | 2014-03-05 | — | — | EP | disclosed |
| US-20140039217-A1 | Process for the Production of 4-Chloroacetoacetyl Chloride, 4-Chloroacetoacetic Acid Esters, Amides and Imides | LONZA LTD (CH) | 2014-02-06 | — | — | US | disclosed |
| WO-2012146604-A1 | PROCESS FOR THE PRODUCTION OF 4-CHLOROACETOACETYL CHLORIDE, 4-CHLOROACETOACETIC ACID ESTERS, AMIDES AND IMIDES | LONZA LTD (CH) | 2012-11-01 | — | — | WO | disclosed |
| EP-2518043-A1 | Process for the production of 4-chloroacetyl chloride, 4-chloroacetic acid esters, amides and imides | Lonza Ltd. (CH) | 2012-10-31 | — | — | EP | disclosed |