Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691775 | 0.78 | TSHR (0.40) | TSHR | |
| SCHEMBL7500204 | 0.78 | CASP1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL3679173 | 0.76 | TSHR (0.38) | TSHR | |
| SCHEMBL5859426 | 0.75 | — | — | |
| SCHEMBL2159347 | 0.73 | — | — | |
| SCHEMBL5861177 | 0.71 | — | — | |
| Water SCHEMBL20546734 | 0.71 | — | — | |
| SCHEMBL11575966 | 0.71 | — | — | |
| SCHEMBL8355251 | 0.70 | KCNN4 (0.33) | — | |
| SCHEMBL13505342 | 0.69 | TSHR (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181087-B1 | PROCESS FOR THE PREPARATION OF ESTERS OF 4-FLUOROSUBSTITUTED 3-OXO-ALCANOIC ACIDS | SOLVAY (BE) | 2015-10-14 | — | — | EP | disclosed |
| US-8481778-B2 | Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids | SOLVAY (SOCIETE ANONYME) (BE) | 2013-07-09 | — | — | US | disclosed |
| US-20110301378-A1 | Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids | SOLVAY (SOCIETE ANONYME) (BE) | 2011-12-08 | — | — | US | disclosed |
| EP-2181087-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 4-FLUOROSUBSTITUTED 3-OXO-ALCANOIC ACIDS | SOLVAY (Société Anonyme) (BE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009021987-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF 4-FLUOROSUBSTITUTED 3-OXO-ALCANOIC ACIDS | Solvay (Société Anonyme) (BE) | 2009-02-19 | — | — | WO | disclosed |